B6db activities : fumi

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	fumi
Description	Hydrolyzed fumonisin B1--pyruvate aminotransferase (2.6.1.-)
Alternative names	HFB1 aminotransferase.
Catalyzed reaction	2-Amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate = 3,5,10,14,15-Pentahydroxy-12,16-dimethylicosane-2-one + L-alanine.
Cofactor	Pyridoxal phosphate.
	Fumonisin B1 is a cancerogenic mycotoxin produced by several species of Fusarium molds, which can contaminate maize, wheat and other cereals. The bacterium Sphingopyxis sp. MTA144 can degrade fumonisin B1. In the degradation pathway, FumI plays a key role by removing the C2-amino group from hydrolyzed fumonisin B1.
Organisms	-Eubacteria
Family	fumi (0)

Links	Enzyme (activities) fumi BRENDA (activities) fumi KEGG (pathways) fumi PLPMDB (PLP mutants) fumi

References	Heinl S, Hartinger D, Thamhesl M, Schatzmayr G, Moll WD, Grabherr R. (2010) An aminotransferase from bacterium ATCC 55552 deaminates hydrolyzed fumonisin B(1) Biodegradation 22 25-30. Heinl S, Hartinger D, Thamhesl M, Vekiru E, Krska R, Schatzmayr G, Moll WD, Grabherr R. (2010) Degradation of fumonisin B1 by the consecutive action of two bacterial enzymes J Biotechnol 145 120-9. Articles on fumi

last changed	2010/11/08 16:28

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