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GABA-T |
| Description |
gamma-aminobutyrate--pyruvate aminotransferase (2.6.1.-) |
| Alternative names |
GABA--pyruvate aminotransferase
4-aminobutyrate--pyruvate aminotransferase
GABA-T |
| Catalyzed reaction |
4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine. |
| Cofactor |
Pyridoxal phosphate. |
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The Arabidopsis enzyme uses preferentially pyruvate, rather than 2-oxoglutarate, as an amino group acceptor and is therefore distinct from EC 2.6.1.19. The sequences are similar to 2.6.1.18 (beta-alanine--pyruvate aminotransferase) and indeed this enzyme, too, is an omega-amino acid--pyruvate aminotransferase. |
| Organisms |
-Plants |
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Family |
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| Links |
Enzyme (activities) GABA-T
BRENDA (activities) GABA-T
KEGG (pathways) GABA-T
PLPMDB (PLP mutants) GABA-T
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| References |
Wu C, Zhou S, Zhang Q, Zhao W, Peng Y.
(2006) Molecular cloning and differential expression of an gamma-aminobutyrate transaminase gene, OsGABA-T, in rice (Oryza sativa) leaves infected with blast fungus J Plant Res 119 663-9. Palanivelu, R.; Brass, L.; Edlund, A.F.; Preuss, D.
(2003) Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels Cell 114 933-41.47-59.. Van Cauwenberghe, O.R.; Makhmoudova, A.; McLean, M.D.; Clark, S.M.; Shelp, B.J.
(2002) Plant pyruvate-dependent gamma-aminobutyrate transaminase:Identification of an Arabidopsis cDNA and its expression in Escherichia coli Can J Bot 80 933-41.. |
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| last changed |
2007/09/17 19:21 |
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