Whole genome analysis
L-cysteine desulfurase/desulfhydrase (4.4.1.-)
L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine
L-Cysteine + H(2)O = pyruvate + H(2)S + NH(3).
The recombinant protein from Mycoplasma pneumoniae is threefold more active as a desulfurase than as a desulfhydrase, but the desulfhydrase reaction seems important for pathogenesis.
PLPMDB (PLP mutants)
Großhennig S, Ischebeck T, Gibhardt J, Busse J, Feussner I, Stülke J (2016)
Hydrogen sulfide is a novel potential virulence factor of Mycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE
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