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B6db activities: l-lysine.2-aminotransferase

Description L-lysine 2-aminotransferase (2.6.1.-)
Alternative names BomE (gene name);
Catalyzed reaction L-lysine + pyruvate = 2-oxo-6-aminohexanoate + L-alanine.
Cofactor Pyridoxal-phosphate.
Other ketoacids can function as acceptors of the amino group.
Apparently, the 2-oxo-6-aminohexanoate product readily rearranges to a cyclic, dehydrated form, piperideine-2-carboxylate, which is a precursor in the biosynthesis of some antibiotics.
Organisms -Eubacteria


Links Enzyme (activities) l-lysine_2-aminotransferase
BRENDA (activities) l-lysine_2-aminotransferase
KEGG (pathways) l-lysine_2-aminotransferase
PLPMDB (PLP mutants) l-lysine_2-aminotransferase
References Articles on l-lysine.2-aminotransferase
last changed 2018/02/16 18:43

B6db activities