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lmbs |
Description |
GDP-D-α-D-lincosamide aminotransferase (2.6.1.-) |
Alternative names |
CcbS (gene name);
LmbS (gene name)
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Catalyzed reaction |
GDP-D-α-D-lincosamide + 2-oxoglutarate <=> GDP-6-oxo 6(1-hydroxyethyl)galactose + glutamate |
Cofactor |
Pyridoxal phosphate. |
Comments |
GDP-D-α-D-lincosamide [i.e., GDP-6-amino 6(1-hydroxyethyl)galactose] is an intermediate in the formation of lyncomycin antibiotics in Streptomyces lincolnensis.
The enzyme LmbS (and also its homolog CcbS, from the Celesticetin biosynthesis pathway) catalyzes the reaction in the direction opposite to the one shown above. |
Organisms |
-Eubacteria |
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Links |
Enzyme (activities) lmbs
BRENDA (activities) lmbs
KEGG (pathways) lmbs
PLPMDB (PLP mutants) lmbs
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References |
Articles on lmbs |
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last changed |
2020/11/04 15:48 |
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