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pctv |
Description |
3-aminobenzoate synthase (2.6.1.-) |
Alternative names |
3-aminobenzoic acid synthase;
PctV (gene name);
PtmT (gene name); |
Catalyzed reaction |
3-dehydroshikimate + L-glutamate = 3-aminobenzoate + 2-ketoglutarate + 2 H(2)O |
Cofactor |
Pyridoxal-phosphate. |
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A PLP-dependent aminotransferase PctV, encoded in the pactamycin biosynthetic gene cluster, was found to catalyze the formation of 3-aminobenzoate from 3-dehydroshikimate with L-glutamate as the amino donor. The PctV reaction comprises a transamination and two dehydration reactions. This is the first report of a simple 3-ABA synthase in nature. |
PDB |
4ZM3; |
Organisms |
-Eubacteria |
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Family |
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Links |
Enzyme (activities) pctv
BRENDA (activities) pctv
KEGG (pathways) pctv
PLPMDB (PLP mutants) pctv
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References |
Articles on pctv |
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last changed |
2019/12/16 14:12 |
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