|
|
| |
pgat |
| Description |
Phenylglycine aminotransferase (2.6.1.-) |
| Alternative names |
L-phenylglycine transaminase.
PglE (gene name; ambiguous); |
| Catalyzed reaction |
phenylglyoxylate + L-tyrosine = L-phenylglycine + 4-hydroxyphenylpyruvate
|
| Cofactor |
Pyridoxal-phosphate. |
| Comments |
L-Phe can also serve as the amino group donor (yielding phenylpyruvate as a product). |
| |
The enzyme from Streptomyces pristinaespiralis is involved in the biosynthesis of the antibiotic pristinamycin PI. |
| Organisms |
-Eubacteria |
| | |
|---|
| | |
|---|
| Links |
Enzyme (activities) pgat
BRENDA (activities) pgat
KEGG (pathways) pgat
PLPMDB (PLP mutants) pgat
|
| | |
|---|
| References |
Osipenkov N, Kulik A, Mast YJ
(2018) Characterization of the phenylglycine aminotransferase PglE from Streptomyces pristinaespiralis J Biotechnol 278 34-38. Liu SP, Liu RX, El-Rotail AA, Ding ZY, Gu ZH, Zhang L, Shi GY
(2014) Heterologous pathway for the production of L-phenylglycine from glucose by E. coli J Biotechnol 186 91-7. Mast YJ, Wohlleben W, Schinko E.
(2011) Identification and functional characterization of phenylglycine biosynthetic genes involved in pristinamycin biosynthesis in Streptomyces pristinaespiralis J Biotechnol 155 63-7. |
| | |
|---|
| last changed |
2018/05/14 09:45 |
|
Browse:
Analyse:
Find: