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B6db activities: pydd

Description Beta-alanine aminotransferase (2.6.1.-)
Alternative names Beta-alanine:2-oxoglutarate aminotransferase;
PydD (gene name)
Catalyzed reaction Beta-alanine + 2-oxoglutarate = 3-oxopropanoate + L-glutamate.
Cofactor Pyridoxal-phosphate.
Involved in the reductive degradation of pyrimidine bases by some bacteria.

The enzyme reacts inefficiently with pyruvate, in contrast with EC (Beta-alanine--pyruvate aminotransferase).

Sequences are closely related to those of taurine aminotransferase (EC; substrate specificities are also largely overlapping.

Organisms -Eubacteria


pydd (0)
Links Enzyme (activities) pydd
BRENDA (activities) pydd
KEGG (pathways) pydd
PLPMDB (PLP mutants) pydd
 Yin J, Wei Y, Liu D, Hu Y, Lu Q, Ang EL, Zhao H, Zhang Y (2019) An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine J Biol Chem 294 15662-15671.

Articles on pydd
last changed 2019/09/12 14:47

B6db activities