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B6db activities: redl

Description 2-undecyl-4-pyrrolinone synthase (2.3.1.-)
Alternative names RedL (gene name)
Catalyzed reaction L-glycine + 3-ketomyristoyl-ACP = 2-undecyl-4-pyrrolinone + CO(2) + ACP + H(2)O
Cofactor Pyridoxal phosphate
Comments The enzyme is a multi-domain enzyme involved in the synthesis of undecylprodigiosin. The C terminus domain of this protein is an α-oxoamine synthase (OAS). The domain catalizes a condensation reaction on glycine, followed by decarboxylation and cyclization, to generate 2-undecyl-4-pyrrolinone.
Organisms -Eubacteria


redl (0)
Links Enzyme (activities) redl
BRENDA (activities) redl
KEGG (pathways) redl
PLPMDB (PLP mutants) redl
 Mo S, Sydor PK, Corre C, Alhamadsheh MM, Stanley AE, Haynes SW, Song L, Reynolds KA, Challis GL (2008) Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis Chem Biol. 15 137-48.

Articles on redl
last changed 2019/01/21 13:45

B6db activities