tuzn1299
Description	Branched chain amino acid--pyruvate transaminase (low-specificity) (2.6.1.-)
Alternative names	TUZN1299 (gene name); VMUT0738 (gene name);
Catalyzed reaction	4-methyl-2-oxovalerate+alanine = leucine+ pyruvate
Cofactor	Pyridoxal-phosphate
	TUZN1299 was found to be highly active toward branched-chain amino acids (BCAAs), positively charged amino acids, l-methionine, l-threonine, l-homoserine, l-glutamine, as well as toward 2-oxobutyrate and keto analogs of BCAAs, whereas l-glutamate and α-ketoglutarate were not converted in the overall reaction. (This is a striking difference with respect to classic BCAATs, grouped in family 2.6.1.42_a)
PDB	5CE8:;
Organisms	-Archea
Links	Enzyme (activities) tuzn1299 BRENDA (activities) tuzn1299 KEGG (pathways) tuzn1299 PLPMDB (PLP mutants) tuzn1299
References	Articles on tuzn1299
last changed	2019/06/20 13:28