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B6db activities: tuzn1299

tuzn1299
Description Branched chain amino acid--pyruvate transaminase (low-specificity) (2.6.1.-)
Alternative names TUZN1299 (gene name);
VMUT0738 (gene name);
Catalyzed reaction 4-methyl-2-oxovalerate+alanine = leucine+ pyruvate
Cofactor Pyridoxal-phosphate
TUZN1299 was found to be highly active toward branched-chain amino acids (BCAAs), positively charged amino acids, l-methionine, l-threonine, l-homoserine, l-glutamine, as well as toward 2-oxobutyrate and keto analogs of BCAAs, whereas l-glutamate and α-ketoglutarate were not converted in the overall reaction. (This is a striking difference with respect to classic BCAATs, grouped in family 2.6.1.42_a)
PDB 5CE8:;
Organisms -Archea
 
 
Links Enzyme (activities) tuzn1299
BRENDA (activities) tuzn1299
KEGG (pathways) tuzn1299
PLPMDB (PLP mutants) tuzn1299
 
References Articles on tuzn1299
 
last changed 2019/06/20 13:28

B6db activities