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B6db activities: asmd

asmd
Description glycyl-[PCP acyl-carrier protein] hydroxymethyltransferase (2.1.2.-)
Alternative names AsmD (gene name);
Catalyzed reaction glycyl-[PCP acyl-carrier protein] + 5,10-methylenetetrahydrofolate + H(2)O = seryl-[PCP acyl-carrier protein] + tetrahydrofolate
Cofactor Pyridoxal-phosphate
Comments Activity involved in the production of two novel cyclopeptides, ashimides A and B, in Streptomyces sp. NA03103
Organisms -Eubacteria
 

Family 

asmd (1)
 
Links Enzyme (activities) asmd
BRENDA (activities) asmd
KEGG (pathways) asmd
PLPMDB (PLP mutants) asmd
 
References
 Shi J, Zeng YJ, Zhang B, Shao FL, Chen YC, Xu X, Sun Y, Xu Q, Tan RX, Ge HM (2019) Comparative genome mining and heterologous expression of an orphan NRPS gene cluster direct the production of ashimides Chem Sci 10 3042-3048.

Articles on asmd
 
last changed 2019/04/29 14:45

B6db activities