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B6db activities: crmg

Description 4-hydroxy-2,2'-bipyridine-6-carbaldehyde aminotransferase (2.6.1.-)
Catalyzed reaction 4-hydroxy-2,2'-bipyridine-6-carbaldehyde + L-glutamate = 6-(aminomethyl)-2,2'-bipyridin-4-ol + 2-oxoglutarate
Cofactor Pyridoxal phosphate
The enzyme from Actinoalloteichus Sp. Wh1-2216-6 catalyzes a key transamination reaction in the biosynthesis of the potent immunosuppressnat Caerulomycin A.
Organisms -Eubacteria


crmg (0)
Links Enzyme (activities) crmg
BRENDA (activities) crmg
KEGG (pathways) crmg
PLPMDB (PLP mutants) crmg
 Zhu Y, Xu J, Mei X, Feng Z, Zhang L, Zhang Q, Zhang G, Zhu W, Liu J, Zhang C. (2016) Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis. ACS Chem Biol. 11 943-52.

Articles on crmg
last changed 2018/03/07 13:47

B6db activities