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B6db activities: dhpd

Description L-alanine--acetylphosphonate aminotransferase (2.6.1.-)
Catalyzed reaction (1-oxoethyl)phosphonate + L-alanine = (1-aminoethyl)phosphonate + pyruvate
Cofactor Pyridoxal phosphate.
Comments -!- In vivo, in Streptomyces luridus, the reaction is part of the dehydrophos biosynthesis pathway.
The substrate for the reaction, acetylphosphonate, is provided by 1-​amino-​2-​(phosphohydroxy)​ethyl​-phosphonate phospho-lyase (dhph-n).
Organisms -Eubacteria


dhpd (0)
Links Enzyme (activities) dhpd
BRENDA (activities) dhpd
KEGG (pathways) dhpd
PLPMDB (PLP mutants) dhpd
 Bougioukou DJ, Mukherjee S, van der Donk WA (2013) Revisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway Proc Natl Acad Sci U S A 110 10952-7.

Articles on dhpd
last changed 2019/04/02 13:14

B6db activities