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B6db activities: fumi

Description Hydrolyzed fumonisin B1--pyruvate aminotransferase (2.6.1.-)
Alternative names HFB1 aminotransferase.
Catalyzed reaction 2-Amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate = 3,5,10,14,15-Pentahydroxy-12,16-dimethylicosane-2-one + L-alanine.
Cofactor Pyridoxal phosphate.
Fumonisin B1 is a cancerogenic mycotoxin produced by several species of Fusarium molds, which can contaminate maize, wheat and other cereals.
The bacterium Sphingopyxis sp. MTA144 can degrade fumonisin B1. In the degradation pathway, FumI plays a key role by removing the C2-amino group from hydrolyzed fumonisin B1.
Organisms -Eubacteria


fumi (2)
Links Enzyme (activities) fumi
BRENDA (activities) fumi
KEGG (pathways) fumi
PLPMDB (PLP mutants) fumi
 Heinl S, Hartinger D, Thamhesl M, Schatzmayr G, Moll WD, Grabherr R. (2010) An aminotransferase from bacterium ATCC 55552 deaminates hydrolyzed fumonisin B(1) Biodegradation 22 25-30.

 Heinl S, Hartinger D, Thamhesl M, Vekiru E, Krska R, Schatzmayr G, Moll WD, Grabherr R. (2010) Degradation of fumonisin B1 by the consecutive action of two bacterial enzymes J Biotechnol 145 120-9.

Articles on fumi
last changed 2010/11/08 16:28

B6db activities