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B6db activities: mbnn

mbnn
Description N-terminal Leucine transaminase (2.6.1.-)
Alternative names MbnN (gene name);
Catalyzed reaction Peptide with N-terminal leucine + 2-oxoglutarate = peptide with N-terminal deaminated leucine + L-glutamate.
Cofactor Pyridoxal phosphate
Comments The enzyme is involved in production of methanobactin from M. trichosporium OB3b.
Organisms -Eubacteria
 

Family 

mbnn (0)
 
Links Enzyme (activities) mbnn
BRENDA (activities) mbnn
KEGG (pathways) mbnn
PLPMDB (PLP mutants) mbnn
 
References
 Park YJ, Kenney GE, Schachner LF, Kelleher NL, Rosenzweig AC. (2018) Repurposed HisC Aminotransferases Complete the Biosynthesis of Some Methanobactins. Biochemistry. 57 3515-3523.

 Gu W, Baral BS, DiSpirito AA, Semrau JD. (2016) An Aminotransferase Is Responsible for the Deamination of the N-Terminal Leucine and Required for Formation of Oxazolone Ring A in Methanobactin of Methylosinus trichosporium OB3b. Appl Environ Microbiol. 83 e02619-16.

Articles on mbnn
 
last changed 2018/03/08 11:01

B6db activities