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B6db activities: odcp

Description Ornithine decarboxylase paralogue
Alternative names ornithine decarboxylase antizyme inhibitor;
AZIN1 (gene name);
AZIN2 (gene name)
Catalyzed reaction None - This is a nonenzymatic homologue of ornithine decarboxylase.
Comments These metazoan proteins belonging to the fold-type III group were once attributed an arginine decarboxylase function. However, subsequent studies proved that they are not catalytic, but rather regulatory proteins.
Organisms -Metazoa


odcp (0)
Links Enzyme (activities) odcp
BRENDA (activities) odcp
KEGG (pathways) odcp
PLPMDB (PLP mutants) odcp
 Rajput B, Murphy TD, Pruitt KD (2015) RefSeq curation and annotation of antizyme and antizyme inhibitor genes in vertebrates Nucleic Acids Res 43 7270-9.

 Kanerva K, Mäkitie LT, Pelander A, Heiskala M, Andersson LC. (2008) Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase Biochem J 409 187-92.

 López-Contreras AJ, López-Garcia C, Jiménez-Cervantes C, Cremades A, Peñafiel R. (2006) Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity J Biol Chem 281 30896-906.

 Zhu, MY.; Iyo, A.; Piletz, J.E.; Regunathan, S. (2004) Expression of human arginine decarboxylase, the biosynthetic enzyme for agmatine Biochim Biophys Acta 1670 156-64.

 Koguchi K, Kobayashi S, Hayashi T, Matsufuji S, Murakami Y, Hayashi S. (1997) Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor Biochim Biophys Acta 1353 209-16.

Articles on odcp
last changed 2018/07/18 14:45

B6db activities