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B6db activities: pctv

pctv
Description 3-aminobenzoate synthase (2.6.1.-)
Alternative names 3-aminobenzoic acid synthase;
PctV (gene name);
PtmT (gene name);
Catalyzed reaction 3-dehydroshikimate + L-glutamate = 3-aminobenzoate + 2-ketoglutarate + 2 H(2)O
Cofactor Pyridoxal-phosphate.
A PLP-dependent aminotransferase PctV, encoded in the pactamycin biosynthetic gene cluster, was found to catalyze the formation of 3-aminobenzoate from 3-dehydroshikimate with L-glutamate as the amino donor. The PctV reaction comprises a transamination and two dehydration reactions. This is the first report of a simple 3-ABA synthase in nature.
PDB 4ZM3;
Organisms -Eubacteria
 

Family 

pctv (5)
 
Links Enzyme (activities) pctv
BRENDA (activities) pctv
KEGG (pathways) pctv
PLPMDB (PLP mutants) pctv
 
References Articles on pctv
 
last changed 2019/12/16 14:12

B6db activities