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B6db activities: plu3042

Description 3,4-dihydrotyrosine transaminase (2.6.1.-)
Alternative names 3,4-dihydrotyrosine aminotransferase;
Plu3042 (gene name);
Catalyzed reaction 3,4-dihydro-hydroxyphenylpyruvate+glutamine = 3,4-dihydrotyrosine +2-oxoglutaramate
Cofactor Pyridoxal-phosphate
The enzyme from Photorabdus luminescens is required for production of 2,5-Dihydrophenylalanine (H(2)Phe), together with two other enzymes encoded by the same gene cluster (plu30423044).
H(2)Phe is a multipotent nonproteinogenic amino acid, acting as an antimetabolite against many organisms.
Organisms -Eubacteria


plu3042 (0)
Links Enzyme (activities) plu3042
BRENDA (activities) plu3042
KEGG (pathways) plu3042
PLPMDB (PLP mutants) plu3042
 Crawford JM, Mahlstedt SA, Malcolmson SJ, Clardy J, Walsh CT (2011) Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis Chem Biol 18 1102-12.

Articles on plu3042
last changed 2018/04/03 15:10

B6db activities