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B6db activities: pucg

pucg
Description Ureidoglycine--glyoxylate aminotransferase (2.6.1.-)
Catalyzed reaction Ureidoglycine + glyoxylate = oxalurate + glycine
Cofactor Pyridoxal phosphate.
Comments -!- Can also use several keto acids (e.g., 2-oxoglutarate) as amino-group acceptors.
In certain bacteria, the catalyzed reaction is part of the urate degradation pathway.
PDB 3ISL; ; 3NNK;
Organisms -Eubacteria
 

Family 

pucg (15)
 
Links Enzyme (activities) pucg
BRENDA (activities) pucg
KEGG (pathways) pucg
PLPMDB (PLP mutants) pucg
 
References
 French JB, Ealick SE. (2010) Biochemical and structural characterization of a ureidoglycine aminotransferase in the Klebsiella pneumoniae uric acid catabolic pathway. Biochemistry 49 5975-7.

 Ramazzina, I.; Costa, R.; Cendron, L.; Berni, R.; Peracchi, A.; Zanotti, G.; Percudani, R. (2010) An aminotransferase branch point connects purine catabolism to amino acid recycling Nat Chem Biol 6 801-806.

Articles on pucg
 
last changed 2010/08/23 13:29

B6db activities