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B6db activities: pumg

Description Pseudouridine-5'-aldehyde aminotransferase (2.6.1.-)
Alternative names PUA aminotransferase;
PumG (gene name);
sapH (gene name);
Catalyzed reaction an L-amino acid + pseudouridine-5'-aldehyde = a 2-oxoacid + 5'-aminopseudouridine.
Cofactor Pyridoxal-phosphate.
Involved in the biosynthesis of pseudouridimycin, a selective nucleoside-analog inhibitor produced by Streptomyces sp. ID38640
Organisms -Eubacteria


pumg (0)
Links Enzyme (activities) pumg
BRENDA (activities) pumg
KEGG (pathways) pumg
PLPMDB (PLP mutants) pumg
 Sosio M, Gaspari E, Iorio M, Pessina S, Medema MH, Bernasconi A, Simone M, Maffioli SI, Ebright RH, Donadio S (2018) Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics Cell Chem Biol 25 540-549.

Articles on pumg
last changed 2019/06/26 13:07

B6db activities