B6db activities : redl

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	redl
Description	2-undecyl-4-pyrrolinone synthase (2.3.1.-)
Alternative names	RedL (gene name)
Catalyzed reaction	L-glycine + 3-ketomyristoyl-ACP = 2-undecyl-4-pyrrolinone + CO(2) + ACP + H(2)O
Cofactor	Pyridoxal phosphate
Comments	The enzyme is a multi-domain enzyme involved in the synthesis of undecylprodigiosin. The C terminus domain of this protein is an α-oxoamine synthase (OAS). The domain catalizes a condensation reaction on glycine, followed by decarboxylation and cyclization, to generate 2-undecyl-4-pyrrolinone.
Organisms	-Eubacteria
Family	redl (0)

Links	Enzyme (activities) redl BRENDA (activities) redl KEGG (pathways) redl PLPMDB (PLP mutants) redl

References	Mo S, Sydor PK, Corre C, Alhamadsheh MM, Stanley AE, Haynes SW, Song L, Reynolds KA, Challis GL (2008) Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis Chem Biol. 15 137-48. Articles on redl

last changed	2019/01/21 13:45

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