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B6db activities: sant

Description Pyridylhomothreonine aminotransferase (2.6.1.-)
Catalyzed reaction 4-pyridyl-2-oxo-4-hydroxyisovalerate + L-Aspartate = pyridylhomothreonine + oxaloacetate
Cofactor Pyridoxal phosphate
The enzyme sant is an essential protein for nikkomycin biosynthesis of Streptomyces ansochromogenes.
Nikkomycins act as a competitive inhibitors of chitin synthetase and display potent activities against phytopathogenic and human pathogenic fungi.
Organisms -Eubacteria


sant (0)
Links Enzyme (activities) sant
BRENDA (activities) sant
KEGG (pathways) sant
PLPMDB (PLP mutants) sant
 Jia L, Tian Y, Tan H (2007) SanT, a bidomain protein, is essential for nikkomycin biosynthesis of Streptomyces ansochromogenes Biochem Biophys Res Commun 362 1031-6.

Articles on sant
last changed 2019/06/20 13:13

B6db activities