|
type |
Journal Article |
authors |
Hegyesi, H.; Szalai, C.; Falus, A.; Csaba, G. |
title |
The histidine decarboxylase (HDC) gene of Tetrahymena pyriformis is similar to the mammalian one. A study of HDC expression |
journal |
Biosci Rep |
Activity |
4.1.1.22 |
ui |
10888469 |
year |
(1999) |
volume |
19 |
number |
7 |
pages |
73-9. |
| |
keywords |
Animal |
abstract |
RNA was isolated from Tetrahymena pyriformis GL and using human histidine decarboxylase (HDC) gene primers, the RT-PCR product was sequenced. A fraction containing 207 base pairs was compared to the published sequences of prokaryotic and mammalian (rat, mouse and human) HDC cDNA (exons). The HDC-cDNA fraction of Tetrahymena was similar to the mammalian cDNA-s and it was completely different from the prokaryotic HDC-gene. The results indicate the presence of a mammalian-like HDC-gene already in a unicellular eukaryote organism and demonstrates also that the divergence of the prokaryotic-eukaryotic common gene took place already at this low evolutionary level. |
last changed |
2004/05/21 12:17 |
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