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B6db references: 10888469

type Journal Article
authors Hegyesi, H.; Szalai, C.; Falus, A.; Csaba, G.
title The histidine decarboxylase (HDC) gene of Tetrahymena pyriformis is similar to the mammalian one. A study of HDC expression
journal Biosci Rep
ui 10888469
year (1999)
volume 19
number 7
pages 73-9.
keywords Animal
abstract RNA was isolated from Tetrahymena pyriformis GL and using human histidine decarboxylase (HDC) gene primers, the RT-PCR product was sequenced. A fraction containing 207 base pairs was compared to the published sequences of prokaryotic and mammalian (rat, mouse and human) HDC cDNA (exons). The HDC-cDNA fraction of Tetrahymena was similar to the mammalian cDNA-s and it was completely different from the prokaryotic HDC-gene. The results indicate the presence of a mammalian-like HDC-gene already in a unicellular eukaryote organism and demonstrates also that the divergence of the prokaryotic-eukaryotic common gene took place already at this low evolutionary level.
last changed 2004/05/21 12:17

B6db references