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B6db references: 11171191.

type Journal Article
authors Tamura, K.; Nishiura, H.; Mori, J.; Imai, H.
title Cloning and characterization of a cDNA encoding serine palmitoyltransferase in Arabidopsis thaliana
journal Biochem Soc Trans
sel selected
ui 11171191
year (2000)
volume 28
number 6
pages 745-7
keywords Acyltransferases/*genetics/*metabolism
abstract The first and committed step in de novo sphingolipid synthesis is catalysed by serine palmitoyltransferase (EC, which condenses serine and palmitoyl-CoA to form 3-ketosphinganine in a pyridoxal-5'- phosphate-dependent reaction. We have isolated and characterized a cDNA clone from Arabidopsis thaliana that is homologous to yeast and mammalian LCB2. For a functional identification, the A. thaliana homologous cDNA was expressed in Escherichia coli, which resulted in significant production of new sphinganine in E. coli cells.
last changed 2009/01/12 19:20

B6db references