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B6db references: 21948349

type Journal Article
authors Amir, R.; Hacham, Y.; Galili, G.
title Cystathionine gamma-synthase and threonine synthase operate in concert to regulate carbon flow towards methionine in plants
journal Trends Plant Sci
ui 21948349
year (2002)
volume 7
number 4
pages 153-6.
keywords Aspartic Acid/metabolism
abstract The sulfur-containing amino acid methionine is a nutritionally important essential amino acid and is the precursor of several metabolites that regulate plant growth and responses to the environment. Methionine production is largely regulated by cystathionine gamma-synthase, the first specific enzyme for its synthesis. This enzyme competes in a complex manner with threonine synthase, the last enzyme in threonine biosynthesis, for their common substrate O-phosphohomoserine. New genetic and molecular data suggest that methionine synthesis and catabolism are coordinately regulated by novel post-transcriptional and post-translational mechanisms that are associated with a regulatory part within the N-terminal part of cystathionine gamma-synthase.
last changed 2002/11/12 16:17

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