|
type |
Journal Article |
authors |
Amir, R.; Hacham, Y.; Galili, G. |
title |
Cystathionine gamma-synthase and threonine synthase operate in concert to regulate carbon flow towards methionine in plants |
journal |
Trends Plant Sci |
Activity |
4.2.3.1 |
ui |
21948349 |
year |
(2002) |
volume |
7 |
number |
4 |
pages |
153-6. |
| |
keywords |
Aspartic Acid/metabolism |
abstract |
The sulfur-containing amino acid methionine is a nutritionally important essential amino acid and is the precursor of several metabolites that regulate plant growth and responses to the environment. Methionine production is largely regulated by cystathionine gamma-synthase, the first specific enzyme for its synthesis. This enzyme competes in a complex manner with threonine synthase, the last enzyme in threonine biosynthesis, for their common substrate O-phosphohomoserine. New genetic and molecular data suggest that methionine synthesis and catabolism are coordinately regulated by novel post-transcriptional and post-translational mechanisms that are associated with a regulatory part within the N-terminal part of cystathionine gamma-synthase. |
last changed |
2002/11/12 16:17 |
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