|
type |
Journal Article |
authors |
Hirayama A, Eguchi T, Kudo F. |
title |
A single PLP-dependent enzyme PctV catalyzes the transformation of 3-dehydroshikimate into 3-aminobenzoate in the biosynthesis of pactamycin. |
journal |
Chembiochem. |
Activity |
pctv |
Family |
pctv |
sel |
selected |
ui |
23744829 |
year |
(2013) |
volume |
14 |
number |
10 |
pages |
1198-203 |
| |
abstract |
Natural amino donation: A PLP-dependent aminotransferase PctV, encoded in the pactamycin biosynthetic gene cluster, was found to catalyze the formation of 3-aminobenzoate from 3-dehydroshikimate with L-glutamate as the amino donor. The PctV reaction comprises a transamination and two dehydration reactions. This is the first report of a simple 3-ABA synthase in nature. |
last changed |
2014/03/05 12:26 |
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