|
type |
Journal Article |
authors |
Funabashi M, Baba S, Takatsu T, Kizuka M, Ohata Y, Tanaka M, Nonaka K, Spork AP, Ducho C, Chen WC, Van Lanen SG |
title |
Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor |
journal |
Angew Chem Int Ed Engl |
Activity |
lipk |
Family |
lipk |
sel |
selected |
ui |
24014169 |
year |
(2013) |
volume |
52 |
number |
44 |
pages |
11607-11 |
| |
keywords |
actinomycetes; bacterial translocase I inhibitor; gene targeting; nucleoside antibiotics; transaldolase |
abstract |
Rise and shine: Using a gene-targeting approach aimed at identifying potential L-threonine:uridine-5'-transaldolases that catalyze the formation of (5'S,6'S)-C-glycyluridine, a new bacterial translocase I inhibitor was discovered from an actinomycete following fermentation optimization. |
last changed |
2018/11/07 13:28 |
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