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B6db references: 3754226

type Journal Article
authors Simmaco, M.; John, R. A.; Barra, D.; Bossa, F.
title The primary structure of ornithine aminotransferase. Identification of active-site sequence and site of post-translational proteolysis
journal FEBS Lett
Activity 2.6.1.13
Family 2.6.1.13
sel selected
ui 3754226
year (1986)
volume 199
number 1
pages 39-42
 
keywords Amino Acid Sequence
abstract Tentative assignments of functional residues in rat liver mitochondrial ornithine aminotransferase have recently been made using the amino acid sequence deduced from a cDNA clone [(1985) J.Biol.Chem. 260, 12993- 12997]. Partial sequences obtained using the pure mature protein demonstrate that one of these assignments, that of Lys 292 as the residue that binds the coenzyme pyridoxal phosphate, is correct. However, the identification of the Glu 34-Gln 35 bond as the site of post-translational proteolysis is in error. This cleavage occurs instead at Ala 25-Thr 26.
last changed 2009/04/28 09:38

B6db references