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B6db references: 75114689

type Journal Article
authors McFall, E.
title Escherichia coli K-12 mutant forming a temperature-sensitive D-serine deaminase
journal J Bacteriol
ui 75114689
year (1975)
volume 121
number 3
pages 1074-7.
keywords Chromosome Mapping
abstract A single-site mutant of Escherichia coli K-12 able to grow in minimal medium in the presence of D-serine at 30 C but not at 42 C was isolated. The mutant forms a D-serine deaminase that is much more sensitive to thermal denaturation in vitro at temperatures above but not below 47 C than that of the wild type. No detectable enzyme is formed by the mutant at 42 C, however, and very little is formed at 37 C. The mutant enzyme is probably more sensitive to intracellular inactivation at high temperatures than the wild-type enzyme. The mutation lies in the dsdA region. The mutant also contains a dsdO mutation, which does not permit hyperinduction of D-serine deaminase synthesis.
last changed 2002/11/18 16:09

B6db references