|
type |
Journal Article |
authors |
Noguchi, T.; Nakatani, M.; Minatogawa, Y.; Morimoto, M.; Kido, R. |
title |
Subcellular distribution and properties of kynurenine pyruvate transaminase in rat kidney |
journal |
Hoppe Seylers Z Physiol Chem |
Activity |
2.6.1.7 |
ui |
76023766 |
year |
(1975) |
volume |
356 |
number |
8 |
pages |
1245-50. |
| |
keywords |
Cytosol/enzymology |
abstract |
Kynurenine transaminase activity in rat kidney was found in both the mitochondrial and supernatant fractions. These fractions contained (a) kynurenine pyruvate transaminase, which showed a preference for pyruvate as amino acceptor, and had a pH optimum between 8.0 and 8.5, and (b) kynurenine 2-oxoglutarate transaminase, with a preference for 2- oxoglutarate and a pH optimum between 6.0 and 6.5. The apparent Km value of the former enzyme for L-kynurenine was much lower than that of the latter enzyme. |
last changed |
2002/11/12 16:17 |
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