|
type |
Journal Article |
authors |
Kido, R.; Noguchi, T. |
title |
Kynurenine pyruvate transaminase and its specific inhibitor in rat intestine |
journal |
Acta Vitaminol Enzymol |
Activity |
2.6.1.7 |
ui |
78100145 |
year |
(1975) |
volume |
29 |
number |
1-6 |
pages |
310-2 |
| |
keywords |
Animal |
abstract |
Kynurenine pyruvate transaminase was partially purified and characterized. The enzyme catalysed the conversion of L-knurenine to kynurenic acid. Transamination rates of 3-hydroxy-DL-kynurenine and 5- hydroxy-DL-kynurenine by the enzyme were 1/2.9 and 1/2.6 of kynurenine. The enzyme showed a higher preference for pyruvate than 2-oxoglutarate as aminoacceptor. The pH optimum of the reaction was 8.0 and 8.5. It was shown that the inhibitor of kynurenine pyruvate transaminase was present in the intestine. |
last changed |
2002/11/12 16:17 |
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