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B6db references: 78100145

type Journal Article
authors Kido, R.; Noguchi, T.
title Kynurenine pyruvate transaminase and its specific inhibitor in rat intestine
journal Acta Vitaminol Enzymol
ui 78100145
year (1975)
volume 29
number 1-6
pages 310-2
keywords Animal
abstract Kynurenine pyruvate transaminase was partially purified and characterized. The enzyme catalysed the conversion of L-knurenine to kynurenic acid. Transamination rates of 3-hydroxy-DL-kynurenine and 5- hydroxy-DL-kynurenine by the enzyme were 1/2.9 and 1/2.6 of kynurenine. The enzyme showed a higher preference for pyruvate than 2-oxoglutarate as aminoacceptor. The pH optimum of the reaction was 8.0 and 8.5. It was shown that the inhibitor of kynurenine pyruvate transaminase was present in the intestine.
last changed 2002/11/12 16:17

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