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B6db references: 78100151

type Journal Article
authors Soda, K.; Moriguchi, M.; Tanizawa, K.
title Regulation of the activity of microbial kynureninase by transamination of the enzyme-bound coenzyme
journal Acta Vitaminol Enzymol
ui 78100151
year (1975)
volume 29
number 1-6
pages 335-8
keywords Alanine
abstract Kynureninase was purified to homogeneity from the extracts of Pseudomonas marginalis and Neurospora crassa. The active kynureninase containing pyridoxal 5'-phosphate transaminates with L-ornithine or L- alanine to form the inactive pyridoxamine 5'-phosphate form of enzyme and delta1-pyrroline-2-carboxylate or pyruvate. This inactive enzyme transaminates with pyruvate to restore the active pyridoxal 5'- phosphate enzyme and L-alanine. The activity of kynureninase is regulated in this manner by transamination of the coenzyme moiety.
last changed 2002/11/12 16:17

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