|
type |
Journal Article |
authors |
Ikeda, M.; Okada, M. |
title |
Effect of pyridoxine deficiency on ornithine aminotransferase in rat kidney and liver |
journal |
J Nutr Sci Vitaminol (Tokyo) |
Activity |
2.6.1.13 |
ui |
86199000 |
year |
(1985) |
volume |
31 |
number |
6 |
pages |
553-61. |
| |
keywords |
Animal |
abstract |
The hepatic and renal activities of ornithine aminotransferase (OAT) [L- ornithine 2-oxoacid aminotransferase, EC 2.6.1.13] were determined in male and female rats given diet with or without pyridoxine. OAT activities were measured in the presence of pyridoxal phosphate. Diet without pyridoxine caused a decrease in hepatic OAT activity in males and no change in females and an increase in renal OAT activity in males and a decrease in females. The increased renal OAT activity in males was associated with increased immunochemically recognizable OAT, and was due to increased synthesis of OAT as shown by measurement of [3H]leucine incorporation in vivo. Thus OAT is regulated by nutritional conditions in different ways in liver and kidney. |
last changed |
2002/11/04 17:41 |
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