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B6db references: 86199000

type Journal Article
authors Ikeda, M.; Okada, M.
title Effect of pyridoxine deficiency on ornithine aminotransferase in rat kidney and liver
journal J Nutr Sci Vitaminol (Tokyo)
ui 86199000
year (1985)
volume 31
number 6
pages 553-61.
keywords Animal
abstract The hepatic and renal activities of ornithine aminotransferase (OAT) [L- ornithine 2-oxoacid aminotransferase, EC] were determined in male and female rats given diet with or without pyridoxine. OAT activities were measured in the presence of pyridoxal phosphate. Diet without pyridoxine caused a decrease in hepatic OAT activity in males and no change in females and an increase in renal OAT activity in males and a decrease in females. The increased renal OAT activity in males was associated with increased immunochemically recognizable OAT, and was due to increased synthesis of OAT as shown by measurement of [3H]leucine incorporation in vivo. Thus OAT is regulated by nutritional conditions in different ways in liver and kidney.
last changed 2002/11/04 17:41

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