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B6db references: 87326410

type Journal Article
authors Martel, A.; Bouthier de la Tour, C.; Le Goffic, F.
title Pyridoxal 5'phosphate binding site of Escherichia coli beta cystathionase and cystathionine gamma synthase comparison of their sequences
journal Biochem Biophys Res Commun
ui 87326410
year (1987)
volume 147
number 2
pages 565-71.
keywords Amino Acid Sequence
abstract The phosphopyridoxyl peptides of beta cystathionase and cystathionine gamma synthase of Escherichia Coli were identified after reduction, carboxymethylation and proteolysis of the holoenzymes. Their comparison with those obtained from rat liver gamma cystathionase (Fearon, C.W., Rodkey, J.A. and Abeles R.H. 1982. Biochemistry 21 3790-3794.) showed a high degree of homology between the three PLP binding sites with the presence of the tripeptide sequence: Thr-Lys(Pxy)-Tyr in their structure. This homology suggests that these enzymes of methionine metabolism have probably the same origin.
last changed 2003/03/17 15:02

B6db references