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B6db references: 89066784

type Journal Article
authors Otsuka, A. J.; Buoncristiani, M. R.; Howard, P. K.; Flamm, J.; Johnson, C.; Yamamoto, R.; Uchida, K.; Cook, C.; Ruppert, J.; Matsuzaki, J.
title The Escherichia coli biotin biosynthetic enzyme sequences predicted from the nucleotide sequence of the bio operon
journal J Biol Chem
ui 89066784
year (1988)
volume 263
number 36
pages 19577-85.
keywords 5-Aminolevulinate Synthetase/genetics
abstract The nucleotide sequence of the biotin (bio) biosynthetic operon of Escherichia coli has been determined. The 5.8-kilobase region contains the five biotin operon genes, bioA, B, F, C, and D. and an open reading frame of unknown function. The operon is negatively regulated and divergently transcribed from a control region between the bioA and bioB genes. The product of the bioA gene, 7,8-diaminopelargonic acid aminotransferase, was discovered to be related to ornithine aminotransferase. The product of the bioF gene, 7-keto-8- aminopelargonic acid synthetase, was found to be similar to 5- aminolevulinic acid synthetase.
last changed 2002/11/12 16:17

B6db references