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B6db references: 94264409

type Journal Article
authors Ishida, M.; Kawashima, H.; Sato, K.; Hashiguchi, K.; Ito, H.; Enei, H.; Nakamori, S.
title Factors improving L-threonine production by a three L-threonine biosynthetic genes-amplified recombinant strain of Brevibacterium lactofermentum
journal Biosci Biotechnol Biochem
ui 94264409
year (1994)
volume 58
number 4
pages 768-70.
keywords Brevibacterium/enzymology/genetics/*metabolism
abstract When a Brevibacterium lactofermentum L-threonine producer that accumulated L-lysine as well, was transformed with a recombinant plasmid carrying the indigenous hom, thrB, and thrC genes, delayed growth and plasmid instability were observed. Addition of organic nutrients, vitamins (thiamine.HCl and d-biotin), and NaCl under the optimal culture conditions solved these problems and further increased threonine production in a small jar fermentor.
last changed 2002/11/12 16:17

B6db references