type	Journal Article
authors	Simmaco, M.; John, R. A.; Barra, D.; Bossa, F.
title	The primary structure of ornithine aminotransferase. Identification of active-site sequence and site of post-translational proteolysis
journal	FEBS Lett
Activity	2.6.1.13
Family	2.6.1.13.a
sel	selected
ui	3754226
year	(1986)
volume	199
number	1
pages	39-42
keywords	Amino Acid Sequence
abstract	Tentative assignments of functional residues in rat liver mitochondrial ornithine aminotransferase have recently been made using the amino acid sequence deduced from a cDNA clone [(1985) J.Biol.Chem. 260, 12993- 12997]. Partial sequences obtained using the pure mature protein demonstrate that one of these assignments, that of Lys 292 as the residue that binds the coenzyme pyridoxal phosphate, is correct. However, the identification of the Glu 34-Gln 35 bond as the site of post-translational proteolysis is in error. This cleavage occurs instead at Ala 25-Thr 26.
last changed	2018/01/23 11:08