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B6db references: 4504380

type Journal Article
authors Gonzalez-Porque, P.; Strominger, J.L.
title Introducting of the 3-deoxy group in 3,6-dideoxyhexoses: a novel cofactor function for pyridoxamine-5'-phosphate
journal Proc Natl Acad Sci U S A
sel selected
ui 4504380
year (1972)
volume 69
number 6
pages 1625-8
abstract A cofactor needed for the reduction of CDP-4-keto-6-deoxy-D-glucose to CDP-4-keto-3,6-dideoxy D-glucose has been detected and purified. Its spectra in neutral, acid, and basic solutions, its behavior on thin-layer chromatography, and other properties led to its identification as pyridoxamine-5′-phosphate. Moreover, authentic pyridoxamine-5′-phosphate substituted for the purified cofactor with about the same specific activity. Other vitamin B6 derivatives did not stimulate the reaction, and inhibition was observed with some of them.
last changed 2009/05/05 11:54

B6db references