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B6db references: 5332731.

type Journal Article
authors Matsuhashi, M.; Strominger, J.L.
title Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B.
journal J Biol Chem
ui 5332731
year (1966)
volume 241
pages 4738-44.
keywords Metabolism
abstract A pyridoxal phosphate-requiring transaminase which catalyzes a reversible reaction between thymidine diphosphate 4-keto-6-deoxy-n-glucose and L-glutamate to form TDP-4-amino-4,6-dideoxy-u-glucose and cY-ketoglutarate has been purified 28-fold from an extract of Escherichia coli strain B. Some properties of the enzyme are reported. Transaminase activity is widely distributed among strains of E. coli, Salmonella, and Pasteurella pseudofuberculosis, but among the organisms studied only E. coli strain B has a transaminase which catalyzes the synthesis of TDP-4- amino-4,6-dideoxy-n-glucose. The other organisms have an enzyme which catalyzes the synthesis of the nucleotide containing the sugar with the n-galacto configuration.
last changed 2007/11/15 18:48

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