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B6db families: 2.3.1.29

2.3.1.29
Activity 2.3.1.29
Description Glycine C-acetyltransferase.
Notes A very compact family, built around the functionally validated sequences from E. coli and metazoa.
PDB 1FC4;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
15
Sequences in seed alignment
BacteriaNP_932000 (Photorhabdus luminescens); CAC46895 (Sinorhizobium meliloti); KBL_ECOLI (Escherichia coli); NP_901320 (Chromobacterium violaceum); ZP_00221545 (Burkholderia cepacia); KBL_SALTY (Salmonella typhimurium); CAB71247 (Streptomyces coelicolor A3(2)); CAG20136 (Photobacterium profundum); NP_904776 (Porphyromonas gingivalis);
MetazoaKBL_MOUSE (Mus musculus); XP_345857 (Rattus norvegicus); AAH47258 (Xenopus laevis); NP_648509 (Drosophila melanogaster); CAA94376 (Caenorhabditis elegans); KBL_HUMAN (Homo sapiens);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence KBL_ECOLI
Domain interval 42-387
Catalytic site 244 K
 
References
 Schmidt, A.; Sivaraman, J.; Li, Y.; Larocque, R.; Barbosa, J.A.; Smith, C.; Matte, A.; Schrag, J.D.; Cygler, M. (2001) Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism Biochemistry 40 5151-60.

 Edgar, A. J.; Polak, J. M. (2000) Molecular cloning of the human and murine 2-amino-3-ketobutyrate coenzyme A ligase cDNAs Eur J Biochem 267 1805-12.

 Aronson, B.D.; Ravnikar, P.D.; Somerville, R.L. (1988) Nucleotide sequence of the 2-amino-3-ketobutyrate coenzyme A ligase (kbl) gene of E. coli Nucleic Acids Res 16 3586-7.

Articles on 2.3.1.29
last changed 2008/02/15 15:08

B6db families