Activities | Families | Sequences | Fold types | References | Help
B6db families: 2.3.1.50.a

2.3.1.50 a
Activity 2.3.1.50
Description Serine C-palmitoyltransferase. (family a)
Notes Note: LCB1 itself IS NOT PLP-DEPENDENT, although it is homologous to PLP-dependent enzymes and forms a complex with the PLP-dependent subunit, LCB2.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
14
Sequences in seed alignment
FungiXP_001879757 (Laccaria bicolor); AAK40365 (Aspergillus nidulans); LCB1_YEAST (Saccharomyces cerevisiae); CAA18397 (Schizosaccharomyces pombe); EEQ36885 (Clavispora lusitaniae);
MetazoaEAA07184 (Anopheles gambiae str. PEST); T25557 (Caenorhabditis elegans); LCB1_CRIGR (Cricetulus griseus); LCB1_MOUSE (Mus musculus); AAF58417 (Drosophila melanogaster); LCB1_HUMAN (Homo sapiens);
ViridiplantaeAC069158 (Oryza sativa); BAB60898 (Arabidopsis thaliana); CAO67084 (Vitis vinifera);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence LCB1_YEAST
Domain interval 145-454
Catalytic site n/a
 
References
 Hanada, K. (2003) Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism Biochim Biophys Acta 1632 16-30.

Articles on 2.3.1.50.a
last changed 2008/10/23 12:23

B6db families