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B6db families: a
Description Ornithine--oxo-acid aminotransferase (family a)
Notes The enzyme from Penicillium chrysogenum employs as substrates both L-ornithine (yielding L-glutamate 5-semialdehyde) and L-lysine (yielding L-aminoadipate semialdehyde). The latter reaction is important for the biosynthesis of penicillin. Given its structural similarity to classic ornithine aminotransferases, and its preference for alpha-ketoglutarate as an amino acceptor, we have included the enzyme from Penicillium in the family, rather than among L-lysine aminotransferases (EC or omega-amino acid--pyruvate aminotransferases (EC
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 0
Reference sequence OAT_HUMAN
Domain interval 61-384
Catalytic site 292 K
References Articles on
last changed 2018/01/23 11:05

B6db families