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B6db families: 2.6.1.28

2.6.1.28
Activity 2.6.1.28
Description Tryptophan--phenylpyruvate aminotransferase.
Notes This family has been built around the characterized enzyme from Aspergillus (Emericella) nidulans. This fungal enzyme catalyzes the first step in the synthesis of bioactive alkaloids belonging to the bis-indolylquinone family.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
4
Sequences in seed alignment
FungiXP_001523024 (Magnaporthe grisea 70-15); XP_757951 (Ustilago maydis 521); ABU51605 (Emericella nidulans); EAU86022 (Coprinopsis cinerea);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence ABU51605
Domain interval 39-425
Catalytic site 270 K
 
References
 Schneider P, Weber M, Rosenberger K, Hoffmeister D. (2007) A one-pot chemoenzymatic synthesis for the universal precursor of antidiabetes and antiviral bis-indolylquinones Chem Biol 14 635-44.

Articles on 2.6.1.28
last changed 2007/12/17 17:54

B6db families