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B6db families:
Description Pyridoxamine--pyruvate transaminase
Notes This family is based on a single functionally validated sequence from Mesorhizobium.
These enzymes, despite not being strictly speaking B6-dependent (pyridoxal is a product rather than a cofactor) possess a Fold-type I structure, most similar to that of serine--pyruvate aminotransferase (
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Reference sequence Q988B8
Domain interval 42-352
Catalytic site 197 K
 Yoshikane Y, Yokochi N, Yamasaki M, Mizutani K, Ohnishi K, Mikami B, Hayashi H, Yagi T (2008) Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J Biol Chem 283 1120-7.

 Yoshikane Y, Yokochi N, Ohnishi K, Hayashi H, Yagi T (2006) Molecular cloning, expression and characterization of pyridoxamine-pyruvate aminotransferase Biochem J 396 499-507.

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last changed 2017/12/13 13:11

B6db families