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2.6.1.30 |
Activity |
2.6.1.30 |
Description |
Pyridoxamine--pyruvate transaminase |
Notes |
This family is based on a single functionally validated sequence from Mesorhizobium.
These enzymes, despite not being strictly speaking B6-dependent (pyridoxal is a product rather than a cofactor) possess a Fold-type I structure, most similar to that of serine--pyruvate aminotransferase (2.6.1.51). |
PDB |
2Z9X; |
PLP Fold Type |
I |
PLP-dependent Domain |
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Number of sequences |
11 |
Sequences in seed alignment |
|
Reference sequence |
Q988B8 |
Domain interval |
42-352 |
Catalytic site |
197 K |
| |
References |
Yoshikane Y, Yokochi N, Yamasaki M, Mizutani K, Ohnishi K, Mikami B, Hayashi H, Yagi T (2008) Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099 J Biol Chem 283 1120-7. Yoshikane Y, Yokochi N, Ohnishi K, Hayashi H, Yagi T (2006) Molecular cloning, expression and characterization of pyridoxamine-pyruvate aminotransferase Biochem J 396 499-507. Articles on 2.6.1.30 |
last changed |
2017/12/13 13:11 |
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