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B6db families: 2.6.1.34.a

2.6.1.34 a
Activity 2.6.1.34
Description UDP-N-acetylbacillosamine transaminase (family a)
Notes A small family of aminotransferases based on the PglE gene product from Campylobacter.
Belongs to a larger subgroup of enzymes (such as GDP-perosamine synthase, 2.6.1.102) involved in the metabolism of NDP-linked amino sugars.
PDB 1O61;4ZTC;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Reference sequence AF108897
Domain interval 8-381
Catalytic site 184 K
 
References
 Kaundinya CR, Savithri HS, Rao KK, Balaji PV (2018) EpsN from Bacillus subtilis 168 has UDP 2,6-dideoxy 2-acetamido 4-keto glucose aminotransferase activity in vitro Glycobiology 28 802-812.

 Riegert AS, Young NM, Watson DC, Thoden JB, Holden HM (2015) Structure of the external aldimine form of PglE, an aminotransferase required for N,N'-diacetylbacillosamine biosynthesis Protein Sci 24 1609-16.

 Olivier NB, Chen MM, Behr JR, Imperiali B. (2006) In vitro biosynthesis of UDP-N,N'-diacetylbacillosamine by enzymes of the Campylobacter jejuni general protein glycosylation system Biochemistry 45 13659-69.

 Schoenhofen IC, McNally DJ, Vinogradov E, Whitfield D, Young NM, Dick S, Wakarchuk WW, Brisson JR, Logan SM. (2006) Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways J Biol Chem. 281 723-32.

Articles on 2.6.1.34.a
last changed 2019/12/11 18:07

B6db families