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2.6.1.34 a |
Activity |
2.6.1.34 |
Description |
UDP-N-acetylbacillosamine transaminase (family a) |
Notes |
A small family of aminotransferases based on the PglE gene product from Campylobacter. Belongs to a larger subgroup of enzymes (such as GDP-perosamine synthase, 2.6.1.102) involved in the metabolism of NDP-linked amino sugars. |
PDB |
1O61;4ZTC; |
PLP Fold Type |
I |
PLP-dependent Domain |
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Number of sequences |
11 |
Sequences in seed alignment |
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Reference sequence |
AF108897 |
Domain interval |
8-381 |
Catalytic site |
184 K |
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References |
Kaundinya CR, Savithri HS, Rao KK, Balaji PV (2018) EpsN from Bacillus subtilis 168 has UDP 2,6-dideoxy 2-acetamido 4-keto glucose aminotransferase activity in vitro Glycobiology 28 802-812. Riegert AS, Young NM, Watson DC, Thoden JB, Holden HM (2015) Structure of the external aldimine form of PglE, an aminotransferase required for N,N'-diacetylbacillosamine biosynthesis Protein Sci 24 1609-16. Olivier NB, Chen MM, Behr JR, Imperiali B.
(2006) In vitro biosynthesis of UDP-N,N'-diacetylbacillosamine by enzymes of the Campylobacter jejuni general protein glycosylation system Biochemistry 45 13659-69. Schoenhofen IC, McNally DJ, Vinogradov E, Whitfield D, Young NM, Dick S, Wakarchuk WW, Brisson JR, Logan SM. (2006) Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways J Biol Chem. 281 723-32. Articles on 2.6.1.34.a |
last changed |
2019/12/11 18:07 |
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