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B6db families: 2.6.1.5

2.6.1.5
Activity 2.6.1.5
Description Tyrosine aminotransferase.
Notes May overlap with 2.6.1.57
PDB 1BW0;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
20
Sequences in seed alignment
MetazoaEAA06243.1 (Anopheles gambiae str. PEST); ATTY_RAT (Rattus norvegicus); NP_572953 (Drosophila melanogaster); CAE63230 (Caenorhabditis briggsae); AAD45375 (Mustela vison); BAC41146 (Mus musculus); ATTY_HUMAN (Homo sapiens); NP_510454 (Caenorhabditis elegans);
Other_EukaryaATTY_TRYCR (Trypanosoma cruzi); AAG00298 (Trypanosoma rangeli);
ViridiplantaeCAN72828 (Vitis vinifera); AED96434 (Arabidopsis thaliana); ADC45389 (Cucumis melo); ESW05165 (Phaseolus vulgaris); XP_002317481 (Populus trichocarpa); XP_004292022 (Fragaria vesca subsp. vesca); XP_006581072 (Glycine max); XP_003628555 (Medicago truncatula); XP_004146045 (Cucumis sativus); ADD54646 (Bruguiera gymnorhiza);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence ATTY_RAT
Domain interval 71-434
Catalytic site 280 K
 
References
 Riewe D, Koohi M, Lisec J, Pfeiffer M, Lippmann R, Schmeichel J, Willmitzer L, Altmann T. (2012) A tyrosine aminotransferase involved in tocopherol synthesis in Arabidopsis. Plant J 71 850-9.

 Lopukhina, A.; Dettenberg, M.; Weiler, E.W.; Hollander-Czytko, H. (2001) Cloning and characterization of a coronatine-regulated tyrosine aminotransferase from Arabidopsis Plant Physiol 126 1678-87.

 Blankenfeldt, W.; Nowicki, C.; Montemartini-Kalisz, M.; Kalisz, HM.; Hecht, HJ. (1999) Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode Protein Sci 8 2406-17.

 Dietrich, J. B.; Lorber, B.; Kern, D. (1991) Expression of mammalian tyrosine aminotransferase in Saccharomyces cerevisiae and Escherichia coli. Purification to homogeneity and characterization of the enzyme overproduced in the bacteria Eur J Biochem 201 399-407.

 Grange, T.; Guenet, C.; Dietrich, J.B.; Chasserot, S.; Fromont, M.; Befort, N.; Jami, J.; Beck, G.; Pictet, R. (1985) Complete complementary DNA of rat tyrosine aminotransferase messenger RNA. Deduction of the primary structure of the enzyme J Mol Biol 184 347-50.

Articles on 2.6.1.5
last changed 2007/09/08 13:19

B6db families