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B6db families: b
Description Valine--pyruvate aminotransferase (family b)
Notes In C. glutamicum, the AvtA gene encodes a protein only weakly similar to the E. coli enzyme (subfamily a) and most similar to the archaeal family and to archaeal aspartate aminotransferases (family
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 19
Sequences in seed alignment
BacteriaSMG37356 (Corynebacterium pollutisoli); NP_218082 (Mycobacterium tuberculosis H37Rv); WP_083985591 (Corynebacterium testudinoris); WP_014310784 (Corynebacterium diphtheriae); WP_005522201 (Corynebacterium matruchotii); WP_132680432 (Saccharopolyspora sp. 5K548); WP_033378054 (Corynebacterium lubricantis); AGS35671 (Corynebacterium maris DSM 45190); KXB50121 (Corynebacterium kroppenstedtii); WP_027004412 (Corynebacterium halotolerans); WP_034651032 (Corynebacterium vitaeruminis); EEW50998 (Corynebacterium efficiens YS-314); WP_080796657 (Corynebacterium sp. Marseille-P2417); WP_042622087 (Corynebacterium marinum); SJM66440 (Corynebacterium glutamicum); PVY27378 (Williamsia marianensis); WP_042908904 (Mycobacterium avium); SQB95988 (Clostridium paraputrificum); STC68803 (Corynebacterium pilosum);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence SJM66440
Domain interval 15-363
Catalytic site 216 K
 Jansen RS, Mandyoli L, Hughes R, Wakabayashi S, Pinkham JT, Selbach B, Guinn KM, Rubin EJ, Sacchettini JC, Rhee KY (2020) Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis Nat Commun 11 1960.

 Marienhagen J, Eggeling L. (2008) Metabolic function of Corynebacterium glutamicum aminotransferases AlaT and AvtA and impact on L-valine production Appl Environ Microbiol 187 7457-62.

 Marienhagen J, Kennerknecht N, Sahm H, Eggeling L. (2005) Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum J Bacteriol 187 7639-46.

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last changed 2019/06/20 11:05

B6db families