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|
2.6.1.66 b |
Activity |
2.6.1.66 |
Description |
Valine--pyruvate aminotransferase (family b) |
Notes |
In C. glutamicum, the AvtA gene encodes a protein only weakly similar to the E. coli enzyme (subfamily a) and most similar to the archaeal family 2.6.1.108 and to archaeal aspartate aminotransferases (family 2.6.1.1_b).
|
PLP Fold Type |
I |
PLP-dependent Domain |
|
Number of sequences |
19 |
Sequences in seed alignment |
|
Reference sequence |
SJM66440 |
Domain interval |
15-363 |
Catalytic site |
216 K |
| |
References |
Jansen RS, Mandyoli L, Hughes R, Wakabayashi S, Pinkham JT, Selbach B, Guinn KM, Rubin EJ, Sacchettini JC, Rhee KY (2020) Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis Nat Commun 11 1960. Marienhagen J, Eggeling L. (2008) Metabolic function of Corynebacterium glutamicum aminotransferases AlaT and AvtA and impact on L-valine production Appl Environ Microbiol 187 7457-62. Marienhagen J, Kennerknecht N, Sahm H, Eggeling L. (2005) Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum J Bacteriol 187 7639-46. Articles on 2.6.1.66.b |
last changed |
2019/06/20 11:05 |
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