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B6db families: 2.6.1.66.b

2.6.1.66 b
Activity 2.6.1.66
Description Valine--pyruvate aminotransferase (family b)
Notes In C. glutamicum, the AvtA gene encodes a protein only weakly similar to the E. coli enzyme (subfamily a) and most similar to the archaeal family 2.6.1.108 and to archaeal aspartate aminotransferases (family 2.6.1.1_b).
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Reference sequence SJM66440
Domain interval 15-363
Catalytic site 216 K
 
References
 Jansen RS, Mandyoli L, Hughes R, Wakabayashi S, Pinkham JT, Selbach B, Guinn KM, Rubin EJ, Sacchettini JC, Rhee KY (2020) Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis Nat Commun 11 1960.

 Marienhagen J, Eggeling L. (2008) Metabolic function of Corynebacterium glutamicum aminotransferases AlaT and AvtA and impact on L-valine production Appl Environ Microbiol 187 7457-62.

 Marienhagen J, Kennerknecht N, Sahm H, Eggeling L. (2005) Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum J Bacteriol 187 7639-46.

Articles on 2.6.1.66.b
last changed 2019/06/20 11:05

B6db families