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B6db families: 2.6.1.80

2.6.1.80
Activity 2.6.1.80
Description Nicotianamine aminotransferase
Notes The family has been constructed upon two characterized sequences from Hordeum vulgare. The sequences of these enzymes strongly resemble tyrosine aminotransferases and other plant enzymes involved in secondary metabolism.
Since this activity does not seem to occur in non-graminaceous plants, very similar sequences from other viridiplantae (e.g., Vitis vinifera) have not been included in this family.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
11
Sequences in seed alignment
ViridiplantaeXP_014757025 (Brachypodium distachyon); XP_021310384 (Sorghum bicolor); BAA87053 (Hordeum vulgare); BAA87052 (Hordeum vulgare); BAD23258 (Oryza sativa (japonica cultivar-group)); XP_004952322 (Setaria italica); XP_020161720 (Aegilops tauschii subsp. tauschii); ARQ30112 (Triticum aestivum); BAE86873 (Oryza sativa (japonica cultivar-group)); PAN05722 (Panicum hallii); ARQ30110 (Triticum aestivum);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence BAA87052
Domain interval 78-445
Catalytic site 289 K
 
References
 Beasley JT, Bonneau JP, Johnson AAT (2017) Characterisation of the nicotianamine aminotransferase and deoxymugineic acid synthase genes essential to Strategy II iron uptake in bread wheat (Triticum aestivum L.) PLoS One 12 e0177061.

 Cheng L, Wang F, Shou H, Huang F, Zheng L, He F, Li J, Zhao FJ, Ueno D, Ma JF, Wu P. (2007) Mutation in Nicotianamine Aminotransferase Stimulated the Fe(II) Acquisition System and Led to Iron Accumulation in Rice Plant Physiol 145 1647-57.

 Takahashi, M., Yamaguchi, H., Nakanishi, H., Shioiri, T., Nishizawa, N.K., Mori, S. (1999) Cloning two genes for nicotianamine aminotransferase, a critical enzyme in iron acquisition (Strategy II) in graminaceous plants Plant Physiol 121 947-956.

Articles on 2.6.1.80
last changed 2007/12/13 19:08

B6db families