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B6db families: 2.6.1.83.a

2.6.1.83 a
Activity 2.6.1.83
Description LL-diaminopimelate aminotransferase (family a)
PDB 2Z1Z;2Z20;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
15
Sequences in seed alignment
ArchaeaNP_275195 (Methanothermobacter thermautotrophicus); YP_447955 (Methanosphaera stadtmanae);
BacteriaYP_001551507 (Prochlorococcus marinus); ZP_01853115 (Planctomyces maris DSM 8797); YP_001039489 (Clostridium thermocellum); DAPAT_PARUW (Candidatus Protochlamydia amoebophila); DAPAT_CHLTR (Chlamydia trachomatis);
ViridiplantaeABE84803 (Medicago truncatula); XP_001416567 (Ostreococcus lucimarinus); ABK93412 (Populus trichocarpa); AAR01225 (Oryza sativa); BT013469 (Lycopersicon esculentum); NP_567934 (Arabidopsis thaliana); XP_001693061 (Chlamydomonas reinhardtii); EDQ75781 (Physcomitrella patens);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence NP_567934
Domain interval 91-456
Catalytic site 305 K
 
References
 Graham DE, Huse HK. (2008) Methanogens with pseudomurein use diaminopimelate aminotransferase in lysine biosynthesis FEBS Lett 3582 1369-74.

 Hudson AO, Gilvarg C, Leustek T. (2008) Biochemical and phylogenetic characterization of a novel diaminopimelate biosynthesis pathway in prokaryotes identifies a diverged form of LL-diaminopimelate aminotransferase J Bacteriol 190 3256-63.

 Watanabe N, Cherney MM, van Belkum MJ, Marcus SL, Flegel MD, Clay MD, Deyholos MK, Vederas JC, James MN. (2007) Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia J Mol Biol 371 685-702.

 Hudson AO, Singh BK, Leustek T, Gilvarg C. (2006) An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants Plant Physiol 140 292-301.

 McCoy AJ, Adams NE, Hudson AO, Gilvarg C, Leustek T, Maurelli AT. (2006) L,L-diaminopimelate aminotransferase, a trans-kingdom enzyme shared by Chlamydia and plants for synthesis of diaminopimelate/lysine Proc Natl Acad Sci U S A 103 17909-14.

Articles on 2.6.1.83.a
last changed 2010/12/06 15:46

B6db families