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B6db families: 2.8.1.7.c

2.8.1.7 c
Activity 2.8.1.7
Description Cysteine desulfurase (family c)
Notes Very divergent family of enzymes, apparently occurring only in a few bacteria. The sequences are very distantly relted to (but shorter than) those in family 4.3.1.36.
The prototype, YcfC from Erwinia amylovora, has been implicated in the synthesis of 6-thioguanine.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Reference sequence WP_004156388
Domain interval 18-288
Catalytic site 148 K
 
References
 Hertweck C (2018) Enzymatic Thioamide Formation in Bacterial Antimetabolite Pathway Angew Chem Int Ed Engl 57 11574-11578.

Articles on 2.8.1.7.c
last changed 2020/02/20 14:44

B6db families